【摘要】 <正> 近年来研究证明,丘脑束旁核和尾核的活动与痛觉的产生有密切关系。我们曾报导,丘脑束旁核同时存在着痛兴奋和痛抑制两种神经元。还有资料表明,中枢神经系统某些核团包括尾核都有对伤害性刺激发生兴奋反应和抑制反应的神经元。为了探更多还原

【Abstract】 Electric discharges of nucl.parafascicularis and nucl,caudatus were recorded simultaneously with both glass microelectrodes in 44 rats so as to observe the effect of noxious stimulation of the sciatic nerve and acupuncture of point “Zusanli” on these discharges.Simul taneous discharges of 81 pairs of above two kinds of neurons were recorded in experiments,including discharges of 26 pairs pain-excit- ing neurons(PEN),3pairs of pain-inhibiting neurons(PIN),28 pairs of the both PEN and PIN,and discharges of 24 pairs of other patterns.The results were as follows: 1.The electric activities of PEN and PIN were demonstrated in nucl.caudatus of rats and the firing patterns of these two types of neurons were characteristic without transformation from one to the other. 2.A noxious stimulus might bring about simultaneous excitation of both PEN in nucl.parafascicularis and nucl.caudatus,or the inhibition of PIN in both,or excitation of PEN in one and inhibition of PIN in the other. 3.Acupuncture of “Zusanli” enhanced the electric activities of PIN and reduced those of PEN in both nuclei simultaneously. It is considered that a noxious stimulus might affect electric discharges of PEN or PIN in nucl.parafascicularis and nucl.caudatus simultaneously,and that acupuncture of “Zusanli” could modulate the activities of the two kinds of neurons.更多还原