【摘要】 <正> 良好的生物瓣膜材料除应消除其抗原成分外,还应保证无菌、具备一定的机械强度、柔软性能及防止胶原纤维溶解等不利变化。自1968年Carpentier采用戊二醛保存生物瓣膜材料以来,大量资料证明,它具有降低生物瓣膜抗原性、提高柔软性和耐力性的特点,已为国内外广泛推广使用。但目前对戊二醛保存组织的适宜浓度、温度和时间等意见尚不一致,以致影响临床效果的进一步提高。本实验应用不同浓度的戊二醛在不同温更多还原

【Abstract】 Varied concentrations 0.1%,0.3%,0.5% 0.65%, and 2%, of glutaraldehyde were used for preserving bovine-pericardium for 6～18 months with an attempt to determine a suitable concentration and temperature and effective duration for the pre servation of this material as a tissue valves to be used in clinic. The results showed that the suitable concentrations of glutaraldehyde were 0.3%,0.5%,and 0.65%,the suitable temperature was 4℃ and the effective duration could not be over 9 months. Under these conditions the tissues remained basically normal in color (not yellow), in softness(not hard) as well as in histological structure; the mechanical strength was increased and bacterial contamination of the material was avoided。更多还原