【摘要】 106例由纤维胃镜诊断的消化性溃疡住院病人,其中75例给痢特灵治疗,31例给与胃舒平作为对照组,治疗两周后复查胃镜以观察疗效。治疗组溃疡愈合56例(74.67％),溃疡缩小17例(22.67％),无变化2例(2.66％)。对照组溃疡愈合22例(70.97％),溃疡缩小6例(19.35％),无变化3例(9.68％)。两组的近期疗效无明显差异(P>0.6)。 73例进行了2～4年随访观察,痢特灵治疗组52例。其中4例(7.69％)复发,对照组21例其中7例(33.33％)复发。两组的复发病例数有明显差异(P<0.02)。 痢特灵的远期疗效比对照组为好,痢特灵的作用机制有待研究。更多还原

【Abstract】 106 cases of peptic ulcer, diagnosed by gastroscopy were admitted into the hospital for therapy. 75 cases were treated with furoxone and 31 cases as control were treated with alum. hydroxide Co. The therapeutic effect was evaluated by gastroseopy. After two week’s therapy the results were as following:In the furoxone group, the ulcers of 56 cases(74.6%) were healed, 17 cases(22.6%) became smaller and 2 cases(2.66%) unchanged. In the control group, the ulcers of 22 cases (70.97%) were healed, 6 cases (19.35%) smaller and 3 cases (9.68%) unchanged. There is no significant difference of short-term effect between the two groups(p>0.6).A follow up study has been done for 2—4 years, the results are as following:Among 52 cases of the furoxone treated group: 4 cases(7.69%) relapsed; 21 eases of the control group: 7 cases(33.33%)relapsed. There is significant difference of the numbers of the relapsed cases between the two groups(p<0.02).The long-term therapeutic effect of furoxone is better than the short term one.The mechanism of effect of furoxone is to be investisgated.更多还原