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急性心肌梗塞血管扩张剂的应用——附41例临床小结

The Vasodilator in the Trcatmcnt of Acute Myocardial Infarction-Report of 41 Cases

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【摘要】 本文为急性心肌梗塞合饼心衰及休克41例采用血管扩张剂治疗的经验总结。 全部病例采用持续静脉点滴,硝普钠从6.25~12.5微克/分开始,最大剂量为250微克/分;瑞吉亭或酚妥拉明从0.07~0.1毫克/分开始,最大剂量为0.6毫克/分;硝酸甘油从10微克/分递增到30微克/分。 41例中合併心力衰竭者29例,休克+心衰者12例。三种血管扩张剂的总有效率:心衰组(29/40)为72.5±7.1%;休克组(9/15)为60±12.6%。41例中重度心衰及休克患者27例,死亡8人,病死率为29.6%±8.8% 使用硝普钠超过一周,或剂量>100微克/分,要注意氰化物中毒。

【Abstract】 This paper reports the vasodilator treatment in 41 cases of heart failure and cardiogenic shock complicating acute myocardial infarction. All patients received continuous intravenous administration. Desage of nitroprosside was 6.25--12.5 μg/min to 250 μg/min in maximum; Regitine or phentolamine from 0.07--0.1 mg/min, to 0.6 mg/min in maximum; nitroglycerin from 10 μg/min to 30 μg/min.Of the 41 cases, 29 patients were complicated with heart failure; as well as 12 with cardiogenic shock and heart failure. Total efficacy of these vasodilators were, heart failure group (29/40), 72.5±7.1%; shock group(9/15), 60±12.6%, of the 41 cases, There were 27 patients complicated with severe heart failure and cardiogenic shock, 8 of them died with hospital mortality of 29.6±8.8%The toxicity of cyanide compound must be observed, if the period of using nitroprusside was over one week or the dosage of using was over 100 μg/min.

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