【摘要】 本文报告了14例人体胆汁中的呋苄青霉素、庆大霉素和卡那霉素的浓度测定及其在胆道内排泄过程的观察。实验表明:在人体胆汁中,庆大霉素和卡那霉素的浓度较低;而呋苄青霉素的浓度明显高于血中即刻浓度,且远远超过该药对大肠杆菌的最低有效抑菌浓度,维持有效抑菌浓度的时间也较长。故在治疗重症胆道感染时,如有条件,应当首选此药。更多还原

【Abstract】 The concentration of Fubencillin, Gentamycin and Kanamycin in human bile were determined, and their excretion in biliary tract of fourteen cases reported. This study shows, that the concentration of Gentamycin and Kanamycin in human bile is lower than that of Fubencillin. The concentration of Fubencillin is much higher than its concentration in blood immediately after injection, and exceeds the minimum inhibition concentration (MIC) of E. coli. The effective inhibitory concentration last much longer, therefore, in the treatment of severe infections, the Fubencillin should be the drug of choice.更多还原