【摘要】 以氚-胸腺嘧啶核苷（³H—TdR）体外参入慢性胃炎和胃癌牯膜,用放射自显影术测定细胞周期参数。 胃粘膜的标记率代表上皮细胞的增殖率,标记率随胃粘膜的病变不同而异,与病变部位无关。伴有肠化生的萎缩性胃炎与胃癌在高增殖率和增殖区向表面扩展这两方面部十分相似。 用体外双标记法测定细胞周期参数T₂和T_c。胃癌细胞群体的S期时间较萎缩性胃炎延长。癌旁组织的S期时间较萎缩性胃炎缩短。其意义有待进一步研究。更多还原

【Abstract】 The parameters of cell cycle were measured with ~3H-Thymidine (~3H-TdR) incorporated into epithelial cells of chronic gastritis and gastric cancer cases in vitro by autoradiography.The labelling index was used to measure the proliferating activity of epithelial cells of the stomach. It varied in different diseases of the gastric mucosa. No correlation of the labelling index was found between that of the fundus and of antrum areas. Atrophic gastritis with intestinal metaplasia and gastric cancer were very similar both in their high labelling indices and extent of proliferation spreading to the surface of theThe durations of Ts and Tc of the gastric epithelial cell cycle were measured with double-label procedure. The S-phase of gastric cancer cells were longer than that of the epithelial ceils of atrophic gastritis. The S-phase of tissues in vicinity of cancer was shorter than that of atrophic gastritis. Further investigation is necessary to evaluate the Sphase variations,更多还原