【摘要】 观察16例HBsAg 携带者的血和唾液中的HBsAg动态,唾液排出HBsAg总阳性率81.3％;HBsAg 在血中的滴度和唾液中的排出率之间无显著差异;e-抗原和e-抗体的存在对唾液排抗原率似无直接影响,唾液排出HBsAg一般是稳定的。调查乙型肝炎高发和低发的两个自然村,发现其HBsAg和抗-HBs均有显著差异;在高发村,HBsAg阳性率随年龄增高而下降,抗-HBs阳性率则随年龄而上升。8个家庭共40名成员的资料表明HBsAg家庭聚集现象明显。更多还原

【Abstract】 Studies on HBsAg excretion from saliva in healthy carriers and cpidem-iological pattern of hepatitis B were carried out in two villages near Beijing with different incidences. A total positive rate of HBsAg excretion from saliva of 81.3% (13/16) was obtained and its relation to serum HBsAg titer was insignificant. A similar positive rate of HBsAg excretion from saliva was also found in cases negative for HBeAg or HBeAb. Since the positive rate of HBsAg excretion from saliva in healthy carriers was rather constant, so it played a significant role in spreading hepatitis B.The incidence of hepatitis B in village with high infection rate was also high. A higher incidence of HBsAg carrier was present in 3-10(22.2%) and 20 ( 20.6% ) year-old group and then gradually decreased. The incidence of positive rate for anti-HBs was also high ( 14% ) and increased with age. In village with low infection rate, the incidences of both HBsAg carrier and anti-HBs were relatively lower. The difference between HBsAg distribution in different age groups was insignificant.A higher incidence of family clustering of HBsAg carriers and chronic hepatitis in aged ones ( above sixty ) in village with high infection rate were noticed. Authors suggested that these aged cases of chronic hepatitis served as reservoir of this disease.更多还原