【摘要】 <正> 1956年夏,江苏省扬州市郊有大批雏鹅死亡,经尸体剖检,发现所有死鹅都有相同病变,判断是一种未知的传染病。调查获悉,疫病来源于同一个炕小鹅的炕坊,并知本病前一次大流行是在1948年春。 从尸体取组织接种于鹅胚绒尿腔或膜上,6天即死亡。曾从死胚绒尿液大剂量静脉注射成年鹅,7天后发病,但其症状与病变和雏鹅不同。1961年在该地又发生大流行,更多还原

【Abstract】 An outbreak of enzootic disease occurred in flocks of 5—20-day old goslings in the city of Yangchow, Jiangsu province, in 1956, and a virus was successfully isolated from the tissues of infected gosling.In 1961 a similar virus was isolated again which could reproduce a disease identical to that observed in natural out breaks. The names of Gosling Plague (GP) and Gosling Plague Virus (GPV) were thusgiven to this specific disease and its causative agent.In 1962 anti-gosling plague serum was prepared. After serial passages in developing goose embryos) the virus was gradually attenuated, and a vaccine was obtained from it for prophylaxis of GP. During the period of 1962—1979, about four million female geese were vaccinated with this live attenuated vaccine. Goslings from vaccinated mothers or receiving antiserum prepared with the Jiangsu strains of GPV could successfully withstand challenge with strains of GPV isolated from different parts of China. The Chinese GPV was found to be antigenically similar to the GPV isolated in Vietnam and Hungary.更多还原