【摘要】 <正> 钩端螺旋体病(下简称钩体病)在我国流行较为广泛,影响人民健康甚大。在钩体病疫区常有脑血管损害的病例发生,对其发病机理和病理变化尚不甚清楚。1968年以来,我们先后作本病尸检7例,现综合报告其中4例,并略加探讨。 临床资料摘要 4例皆为儿童,5岁、12岁各1例,9岁2例。病程分别为9天、23天、70余天、2年零11天。均来自农村钩体病疫区,血清学试验(包括补体结合试验及显微镜下凝集试验)2例阳性,2例不详。1例于病变之大脑中动脉内弹力膜内侧增厚之内膜中发现免疫萤光阳性物质。4例全具有脑动脉炎的临床症状和体征,脑血管造影皆呈阳性所更多还原

【Abstract】 This paper presents the autoptical findings of 4 cases of cerebral arteritis. The in-flammative lesion predominantly involves larger arteries of the base of brain - basal cerebral polyarteritis. The main pathological changes are endarteritis proliferans. It may be classified into three types: acute, chronic and obliterosclerous. In 2 cases the specific serological tests for leptospirosis were positive, in l case spirochetes were found in cerebral artery; and in the remaining case immuno-fluorecent positive substance was also found in cerebral arteries. From the above pathological findings and clinicoepidemiolo-gical data, it becomes evident that these 4 cases of cerebral arteritis may result from leptospirocheta infection.更多还原