【摘要】 <正> 根据资料证实,当药物(毒物)引起肝脏病变,受波及的肝细胞常出现不同程度的病理形态学变化,而其细胞和组织化学的变化,又远比细胞一般形态学的变化早出现。因此,借助细胞化学和组织化学的方法去更多还原

【Abstract】 Nithiocyamine is a new schistosomicide,The effects of nithiocyamine on the liver functions were studied by histochemical methods.187 mice used for studying were divided into 6 groups.The experimental results showed,under the influence of nithiocyamine the regular rule seemed to be present concerning changes of activities of PAS reaction.SDH,ATPase,CHE,Acp,ALp;there was an obvious,diminishing of PAS reaction,SDH and ATPase.ChE activity in groups with dosage of 250-500 mg/kg ip while the activities of ACP and ALp were elevated.The results showed while administering large doses of nithiocyamine the liver may be damaged.The clinician must attention be careful in patients with abnormal liver function not to overdose them.更多还原