【摘要】 <正> 新生儿染色体异常发生率的调查,国外已有八个用常规染色体技术、一个用 G 显带技术的调查资料。国内尚无报告。我们自1979年5月3日开始,用染色体 G 式显带技术对长沙市北区三个医院连续出生的新生儿脐血标本作了染色体检查,以探讨中国人群中染色体异常的发生率,至1981年5月19日止共完成2079人的检查,已肯定的染色体异常共15例。他们的核型见表1更多还原

【Abstract】 Investigations on chromosome aberrations of the consecutive liveborn infantshave been reported in the western countries eight by conventional technic and oneby G-banding technic(1,2)We studied the umbilical blood of infants born from May 1979 to May 1981 inthree hospitals of the northern section of Changsha in order to find out the incidenceof the chromosome aberrations of Chinese population.A total of 2079 consecutive live-born babies were karyotyped by the G-banding technique.·The Department of Obstetrics and Gynecology of the First Affiliated Hospital··The specimens were kindly applied by The Department of Obstetrics and Gynecology of theFirst Affiliated Hospital,H.M.C.,Maternity and Child Health Hospital of Hunan Province andThe Department of Obstetrics of the First Munocopal Hospital of Changsha In C.B.No335 Dai family:Altogether six relatives of the propositus his nother,grandfather,one brother,oneaunt,one female cousin and one uncle were found to have similar pericentric inver-sions of chromosome 5.So far as we know,among the 15 cases of chromosome aberrations,Six havenot been seen in the world reports untill 1980(see examination No.552;01588;0764;335;-621 and-58 in the above table with pictures in PP.Ⅰ-Ⅲ in the additional pho-togrlaphie plate,and 12 have not been reported in our country,they are listed inthe table as follows:examination No,335;552;654;988;045;0764;01271(-445);01324;01507;01588;-58 and -621.Besides,118 cases in this mass screen identified primarily by umlilical bloodwere polymorphysm or suspected as chromosome aberrations and 9 cases were foundthat the sex of karyotype were not in correspondence with registered sex of birth.(Pictures are seen in the additional photographic pages at P.Ⅰ、Ⅱ、Ⅲ)更多还原