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肺癌病人免疫功能观察

STUDY ON IMMUNE FUNCTION OF LUNG CANCER PATIENTS

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【作者】 薛彬王莹钱玉崑宗淑珍

【Author】 Xue Bin, Environmental Medieine Laboratory, Beijing Medical College

【机构】 北京医学院卫生系环保室北京医学院微生物教研室北京医学院微生物教研室

【摘要】 <正> 近数十年来,肺癌的发病率和死亡率均有较明显的增长。如美国近十四年来,男性肺癌死亡率增加十八倍,女性增加六倍。上海市1960年肺癌发病率占全部恶性肿瘤的第六位,而1970年则跃后第二位,因此肺癌已成为医学界重点研究课题之一。对肺癌病人免疫功能动态检测,将有助于肺癌的防治。现将有关实验结果报告如下。

【Abstract】 155 cases of lung cancer patients examined with pulmonary cancer associated antigen (PCAA) were presented The positive rates are up to 85.2%. Some cross reactions up to 73% with patients of stomach cancer Normal persons and other cases with chronic diseases are negative. But probloms of purification of antigen and antiserum, false positive and false negative remain to be solved.We analyzed the Protien fractions in serum of lung cancer patients with electrophoresis, and found that α1α2 and γ globulins increased in lung cancer.We also studied the immunoglobulin level in patients with lung cancer, and found that serum IgM is decreased, whereas IgA increased, but in late cases all serum immunoglobulins are decreased.

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