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国产细辛属植物中挥发油的成分鉴定——Ⅰ.辽细辛的挥发油

IDENTIFICATION OF THE CONSTITUENTS OF VOLATILE OILS FROM CHINESE ASARUM SPECIES Ⅰ. VOLATILE OLL FROM LIAO XIXIN, ASARUM HETEROTROPOIDES VAR. MANDSHURICUM

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【作者】 田珍董善年王宝荣楼之岑

【Author】 Tian Zhen, Dong Shan-nian, Wang Bao-rong, Lou Zhi-cen Department of Pharmacy, Beijing Medical College

【机构】 北京医学院药学系北京医学院药学系

【摘要】 <正> 细辛是一种常用中药,功能发散风寒,温经止痛,主治风寒感冒及风寒引起的头痛、肌肉关节痛等,亦常用于治疗牙痛。药理研究表明,细辛的挥发油有解热、镇静、镇痛、降压和局部麻醉等作用。因此,对细辛的挥发油成分进行研究是有意义的。

【Abstract】 More than thirty species of Asarum (family Aristolochiaceae) are indigenous to China, among which many are used in traditional and folk medicine.The volatile oil separated by steam distillation from the dried herb of Asarum heterotropoides Fr. Schmidt var. mandshuricum (Maxim.) Kitagawa known commercially as Liao xixin was analyzed and the constituents identified by GC-MS, some of the constituents were isolated by means of GC and further confirmed by IR, UV and NMR. As a result, nine of the constituents were identified The oil consists mainaly of methyleugenol, the other components in the order of relative abundance are safrole, eucarvone, β-pinene, α-pinene, elemicine, asaricin, estragole and camphene.The presence of asaricin and campbene in this plant has not been reported previously, while α-pinene and β-pinene were reported as α-or β-pinene, and estragole as borneol or estragole.

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