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流行性乙型脑炎早期诊断的研究——特异性乙脑IgM抗体的测定

THE STUDY OF EARLY DIAGNOSIS OF ENCEPHALITIS B THE DETECTION OF ENCEPHALITIS B-SPECIFIC IGM ANTIBODY.

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【作者】 陈伯权; 孙月英; 郁文芳; 刘琴芝;

【Author】 Chen Bo Quan Sun Yue Ying Yue Wen Fang Liu Qin Zhi Institute of Virology, Chinese Aeademy of Medical Sciences.

【机构】 中国医学科学院病毒学研究所; 中国医学科学院病毒学研究所;

【摘要】 本文重点研究了IgM抗体在乙脑早期诊断中的意义。本实验证明乙脑病人在病第2~6天在血中已能查到IgM抗体,经144例双份血清抗体有4倍增长可以确诊为乙脑的患者,有69例急性期单份血清就可以查出IgM抗体,早期诊断率为47.9%,实验还证明国产2-ME(2-巯基乙醇)和70℃加温法可以代替进口2 ME。

【Abstract】 The significance of detecting TgM antibody in the early diagnosis of encephalitis B was examined.It was demonstrated by the experiments that IgM antibody could be detected in the patients’ serum after 2—6 days of onset of the disease. In 144 cases, the diagnosis of encephalitis B was established by 4-fold increase of antibody titre of paired serum samples and, in 69 of these IgM antibody could be detected in single serum samples obtained during the acute stage of the disease. The percentage of early positive diagnosis was 47.9%.It was also shown by the experiments that locally produced 2-ME (2-mercaptoethanol) or the method of 70℃ incubation might be used instead of imported 2-ME.

  • 【文献出处】 北京医学 ,Beijing Medical Journal , 编辑部邮箱 ,1981年03期
  • 【被引频次】16
  • 【下载频次】28
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