【摘要】 用香竺葵油治疗子宫颈癌时发现有清洁组织表面感染的作用.根据此现象,本室应用三种不同方法(纸片、倾注平板和蒸熏法)检测多种细菌对该药的敏感性.结果表明香竺葵油对革兰氏阳性常见化脓菌,如金黄色葡萄球菌、白色葡萄球菌、乙型链球菌、白喉杆菌及枯草杆菌等有较强杀菌作用,而对革兰氏阴性无作用.通过光镜观察香竺葵油可改变枯草杆菌形态呈现多形性,电镜下可见细菌细胞壁有明显缺损脱落.因此认为该药作用机制在于对革兰氏阳性菌细胞壁的糖肽有作用,从而导致细菌裂解死亡.更多还原

【Abstract】 The essence of Pelargonium geraveolens has been shown to have a cleaning effect of the surface infection in the treatment of carcinoma of cervix. On the basis of this phenomenon, we used 3 different methods (paper disc, pour plate and fuming) to test the suseptibility of different organisms to this drug. The results showed that most of the Gram positive pyogenic organisms, e.g. Staphylococcus aureas, Staphylococ cus albus, Streptococcus hemolyticus, Corynebacterium diphtheriae and Bacillus subtilis, etc. were highly susceptible, while the Gram negative organisms were not. In light microscope the B. subtilis became pleomorphic, and in electron microscope the cell wall was peeled off. This drug is considered to have some effect on the peptoglycans of the cell wall of the Gram positive organism.更多还原