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安徽省繁昌县肺吸虫病的流行学及病原生物学研究

Epidemiology of Paragonimiasis and Biology of its Etiologic Agent in Fanchang County, Anhui Province

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【作者】 何毅勋; 黄德生; 胡亚青; 朱雪花; 张永年;

【Author】 Ho Yihsun, Huang Desheng, Hu Yaqing, Zhu Xuehua and Zhang Yongnjan( Institute of Parasitic Diseases, Chinese Academy of Medical Sciences, Shanghai)

【机构】 中国医学科学院寄生虫病研究所; 中国医学科学院寄生虫病研究所 上海; 上海; 上海;

【摘要】 本文报告了安徽繁昌县桃冲山区为肺吸虫病的新流行区。在3201人的肺吸虫皮试中,阳性者364人(占11.4%)。在35名皮试阳性者痰中查出肺吸虫卵,为皖南地区肺吸虫病流行首次提供病原学诊断。对该地区肺吸虫病流行传播的各个环节均已查清,证明短沟蜷为第一中间寄主,自然感染率为0.02%;长江华溪蟹为第二中间寄主,自然感染率为40.5%。根据于该地区查获的肺吸虫各期标本的形态特征和测量结果,认为该地区人体肺吸虫病的病原虫种是卫氏并殖吸虫。

【Abstract】 A survey of paragonimiasis in the hill region of Fanchang county was carried out. Skin test was positive in 364 ( 11.4%)out of 3,201 inhabitants. The incidence for males was 11.1%, and for females 10.8%. Sputum specimens from 155 children positive for skin test were examined and Paragonimus ova were found in 35 cases (22.6%) .The first intermediate host was found to be Semisulcospira sp. 5,154 snails were examined, and the rate of infection being 0.02%.Sinopotamon yantsekiense was found to be the second intermediate host of lung fluke with an infection rate of 40.5%.Artificial infection was carried out on 7 kinds of animal species with Paragonimus cysts, it was found that the flukes matured only in carnivorous hosts such as cat and dog. Ova were found in feces of dogs with an average of 62 days after infection, and 56.3 days in those of cats.The average size of ova obtained from 11 patients was 87.8±6.6×50.7 ±3.0μ. The average size of miracidium was 84.9×47.9μ.The average size of second generation rediae, obtained from infected Semisulcospira,was 614.9±107.5×271.8±48.8μ, and the gut extended beyond the middle of the body. Rediae were elliptical in shape with round posterior end. The body size of microcercus cercariae was 192.2±14.0×108.4±10.8μ, and that of the tail was 23.0±3.3×22.7±2.7μ.The average size of metacercariae was 398.3±32.3×392, 7±33.0μ, Hot including the outer cyst wall, and that of excysted metacercariae was 522.5 ±61.0×329.6+++++++23.1μ, with 60 flame cells.The adult worms were elliptical in shape, with an average size of 11.74 ±1.12×6.70±0.90mm ( from cat ) or 10.46±1.60×6.22±1.04mm ( from dog).Basing on the above-mentioned morphological characteristics, we are of the opinion that this pathogenic lung fluke belongs to Paragonimus westermani.

  • 【文献出处】 中国医学科学院学报 ,Acta Academiae Medicinae Sinicae , 编辑部邮箱 ,1980年01期
  • 【被引频次】10
  • 【下载频次】36
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