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大脑皮层与针刺抑制内脏痛的关系——Ⅳ.内脏痛信号与“内关”传入信号在大脑皮层中的相互作用

Relationship between Cerebral Cortex and AcupunctureInhibiton 6f VisceralgiaIV. Interaction between Visceralgial Signal and Acupunctural Signal in Cerebral Cortex

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【作者】 翁纪伟; 陈助华; 任惠芳; 陈培熹;

【Author】 Wong Jiwei Chan Zohua Ran Haifan Chan Peixi (Department of Physiology, Zhong Shan Medical College)

【机构】 中山医学院生理学教研组; 中山医学院生理学教研组;

【摘要】 <正>针刺镇痛基本上是痛觉传入信号和穴位传入信号在中枢神经系统内相互作用的结果,目前已有大量材料支持这一观点。业已证明,内脏伤害性传入冲动可以到达大脑皮层内脏大神经投射区,引起内脏痛放电和诱发电位。我们还观察到:刺激“内关”穴时,在皮层“内关”投射区出现诱发电位和单位放电,表明“内关”穴位传入信号也可到达大脑皮层。本文进一步探“内关”传入信号是否进入皮层内脏大神经投射区,是否同内脏痛传入信号发生相互作用。

【Abstract】 ( 1 ) whether the afferent signals to "Naiguan" point and visceral pain converge at the cerebral cortex? (2) What is the effect of the interaction of these signals? and(3)Is there any corresponding relationship between acupuncture and these interactions?Experiments were performed on cats, anesthetized with chloralose and urathane and immobilized with flaxedil. Strong electrical pulsation stimuli were used to stimulate the splanchnic nerve so as to elicit visceral pain.Cortical visceralgial unit discharges were recorded with glass microelectrode at the splanchnic nerve projection area of the contralateral cortex, after the visceralgial units are determined. In order to find out the convergence unit, electrical pulsations of medial strength were used to stimulate the "Naiguan" point, and the efferent signal point of the visceralgial unit were observed. Then, both the splanchnic nerve and "Naiguan" point were stimulated simultaneously and the results of the interaction were observed.1. In 34 visceralgial excitatory units of the cerebral cortex, when the "Naiguan" was stimulated, the rate of unit discharge increased in 27 ( termed convergence units), decreased in 3, remained unchanged in 4 (called inconvergence units). The above data showed that the afferent signal of "Naiguan"point could reach the cortical visceralgial excitatory units (convergence in cerebral cortex).2. In 29 convergence units, when both the "Naiguan" point and splanchnic nerve were simultaneously stimulated, visceralgial discharges were reduced in 12 units (convergence inhibition), increased in 9 units (convergence acceleration) and unchanged in 8 units. It was suggested that the interaction of these two afferent signals must be quite complex. It could be inhibition, acceleration or no change at all.3.These observations showed that the effect of acupuncture was closely related to convergence. In convergence inhibitory units,the inhibiting effect of electro-acupuncture on the viscerealgia was obvious, but it was not significant in the convergence acceleratory units.

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