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抗菌素799的化学鉴别

CHEMICAL IDENTIFICATION OF ANTIBIOTIC 799

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【作者】 吴剑波; 赵厚明; 李宝义;

【Author】 Wu Jianbo, Zhao Houming and Li Baoyi (Department of Chemistry, Institute of Antibiotics, Chinese Academy of Medical Sciences. Beijing)

【机构】 中国医学科学院抗菌素研究所化学室; 中国医学科学院抗菌素研究所化学室 北京; 北京; 北京;

【摘要】 本文论述了从链霉菌799的发酵液提取、分离抗菌素799的方法;研究分析了抗菌素799的理化性质,并从化学方面把它与国外用于临床的抗菌素螺旋霉素进行了比较,结果确认:抗菌素799就是螺旋霉素。

【Abstract】 Antibiotic 799 was isolated from the culture fluid of Streptomyces 799. The physical and chemical characteristics of antibiotic 799 were compared with spiramycin produced by S. ambofaciens. Their UV, IR, MS and NMR (1H and 13C) spectra were analysed. On the basis of above data it was concluded that although taxonomially Streptomyces 799 is distinct from S. ambofaciens, the antibiotic-799 and spiramycin produced by them are identical.

  • 【文献出处】 药学学报 ,Acta Pharmaceutica Sinica , 编辑部邮箱 ,1980年11期
  • 【被引频次】8
  • 【下载频次】22
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