【摘要】 <正> 救必应为冬青科植物铁冬青(Ilex rotunda Thunb.)的干燥树皮。为华南地区常用中草药。朱任宏等曾从广西产救必应(Ilex spp.)中获得两种甙类成分,但未报道其化学结构。我们从广东产救必应的乙醇提取物中获得三种结晶性成分,分别暂名为救必应甲素、乙素和丙素。药理实验证明乙素有明显的止血作用。乙素的薄层层析R_f值及显色情况、熔点、紫外及红外光谱与文献报道的救必应甙甲(ilexanin-A)一致;同时与文献报道的祖师麻丙素红外光谱也一致;证明三者为同一物质。经理化实验数据分析证实乙素为丁香甙(Syrin-更多还原

【Abstract】 Jiu Bi Ying, the bark of Ilex rotunda Thunb., is used as medicine in South China. The glucosides, ilexanin A and ilexanin-B, isolated from the bark, have been reported by Zhu Renhong (Chu Jen-hung) et al without describing their structures. This paper reports the isolation and identification of a hemostatic constituent-Crystal B. At the same time, crystal A and C were also obtained and the studies are in progress.Crystal B (Ⅰ) was isolated from an ethanol extract of the bark powder by alumina column chromatography. It was found to be identical with ilexanin-A by comparison between their mp, TLC, UV, MS and IR data.On the basis of IR, MS, NMR and chemical evidences of crystal B (Ⅰ), its acetate and the oxidative products of its aglycone (Ⅲ)(Ⅳ), the structure of crystal B is elucidated as 3,5-dimethexy-4-hydroxy-cinnamic alcohol-4-0-glucoside, i. e. Syringin.更多还原