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仔猪红痢的研究——Ⅱ、菌苗研究及免疫试验

STUDIES ON ENTEROTOXEMIA IN PIGLETS——Ⅱ. Vaccine and Immunization

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【作者】 文希哲王品杰项大实

【Author】 Wen Hsiche Wang Pinchih The Control Institute of Veterinary Bioproducts and Pharmaceuticals, Ministry of Agriculture. Hsing Tashih Beijing Veterinary Service.

【机构】 农业部兽医药品监察所农业部兽医药品监察所北京市畜牧兽医站

【摘要】 1.研究成功一种仔猪红痢菌苗,经试验室试验和实际使用证明菌苗安全,效力显著,已投入大量生产,供防疫使用。 2.注射菌苗的怀孕母猪初乳中,含有大量抗毒素,仔猪通过吃初乳获得坚强的免疫。 3.怀孕母猪注射两次菌苗效力可靠,注射剂量第一次可用5~10ml,第二次用10ml,注射日期,第一次在分娩前一个月前后,第二次在分娩前半个月前后较为适宜。 4.注射一次菌苗如果剂量在10ml以上,时间在分娩前半个月前后,也能收到较好的效果,但如果注射剂量较小,注射日期又距分娩期太近,则将降低菌苗的效力。再加上少数怀孕母猪产生免疫的能力较差,仔猪就会得不到充分的保护,因此以注射两次为宜。 5.菌苗的使用剂量似嫌偏大,有待进一步改进。

【Abstract】 An Enterotoxemia vaccine for new-born piglets has been successfully prepared.The vaccine Was proved safe and immunogenic through experiments in laboratory and field trials. High degree content of antitoxin were found in colostrum of the vaccinated pregnant sows, which confer sound passive immunity to the new-born piglets. As for the vaccination of pregnant sows, two doses were recommended: 5-10 ml. at about 30 days and 10 ml. at 15 days before parturition.Better result was also made by using a single dose of 10 ml. at half month before parturition. It was noted, however, that the effect of vaccination was possibly minimized if too smaller dose and too late from parturition were used, in addition to the poor ability of some sows in immunity producing.

  • 【文献出处】 畜牧兽医学报 ,Chinese Journal of Animal and Veterinary Sciences , 编辑部邮箱 ,1980年01期
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