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应用敞式装置固定大白鼠的针剌镇痛模型
A MODEL OF ACUPUNCTURE ANALGESIA WITH APPLICATION OF THE EXPOSED TYPE APPARATUS FOR RESTRAINING THE RAT
【摘要】 <正> 在针刺镇痛原理和痛觉生理的实验性研究中,大白鼠是被研究和应用得较多的一种动物,有人采取闭式装置,即将动物装入硬质筒内,这样只能使其身体的一部分露于筒外。我们是采用敞式法,将清醒大白鼠比较自然的固定在特制的实验基座上,使其身体的绝大部分敞露于外。这对选择伤害性
【Abstract】 An apparatus of exposed type for restraining the rat in acupuncture analgesia research has beendesigned.During the experiment the rat was restrained on a wooden base having a shallow throughwith two canvas-bands passing over the posterior of the animal’s shoulders and the anterior of thecoxae respectively.In contrast with the commonly used hard tube,the apparatus has the followingadvantages:Most parts of the body surface are exposed,the animal is being kept in natural position,and the respiration remains normal.The restrain is not causing uneasiness,consternation,struggle,gnawing,attack etc.gnawing 260 experiments were performed on 48 rats.A single square wave impulse delivered from theC 64-2 multi-wave therapeutic stimulator was applied to the tail skin of the unanesthetized animals.Thepain response was indicated by tail flick and screaming of the animals.The pain threshold was mea-sured in voltage of stimulation.Acupuncture analgesia was then induced by electricali needling at cer-tain points corresponding to the“Renzhong”point,“Jiaji”points and bilateral“Zusauli”points inman respectively with the repetitive wave impulses which were delivered from the G-6805 therapeuticstimulator.(Continued on p.232 The results of the experiments indicated that after analgesia being induced with electrical needlingat above-mentioned points separately,the mean values of pain threshold increased significantly ascompared with those before electrical needling and of control group.On the other hand,there is nosignificant difference in the effect of acupuncture analgesia among these three poin-groups.The sameexperiments were repeated after an interval of one and half months,the pain threshold values and theeffect of acupuncture analgesia were shown to be relatively stable.
- 【文献出处】 针刺研究 ,Acupuncture Research , 编辑部邮箱 ,1980年03期
- 【被引频次】9
- 【下载频次】30