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颈动脉内注射单胺类物质对猫皮层诱发电位的抑制作用

INHIBITORY EFFECTS OF INTRACAROTID INJECTIONS OF MONOAMINES ON THE CORTICAL SPLANCHNIC EVOKED POTENTIALS

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【作者】 郑永芳; 陈孟勤; 张宝珍;

【Author】 Zheng Yongfang Chen Mengqin Zhang Baozhen (Department of Physiology,Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences,Beijing)

【机构】 中国医学科学院基础医学研究所生理学研究室; 中国医学科学院基础医学研究所生理学研究室;

【摘要】 <正> 在过去的交叉循环实验中曾提示外周单胺类物质可能参与了电针供血猫对刺激未受针刺的受血猫内脏大神经引起的皮层诱发电位的抑制效应。随后又采用血浴器官生物测定法初步证实电针穴位确能促使猫外周单胺类物质的释放。本工作进一步观察从颈动脉注射单胺类物质对平均迭加的皮层

【Abstract】 The inhibitory effects of intracarotid injections of serotonin,nor-adrenaline or adrenaline indifferent doses on averaging cortical splanchnic evoked potentials,indicating the central pain response,were observed in 27 cats.Furthermore,combination of intracarotid injection of noradrenaline in sub-effective dose and electro-needling the acupoint “Weishu” with low intensity had a facilitating effecton the inhibition.The results suggest that the monoamines in peripheral circulation may enter thebrain and inhibit the cortical electroactivity,and may have a facilitating effect on acupunctureanalgesia.This work supports the results observed in our previous cross-circulation experiments,i.e.humoral factors play a role in the central action of acupuncture analgesia.

  • 【文献出处】 针刺研究 ,Acupuncture Research , 编辑部邮箱 ,1980年01期
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