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心性猝死51例临床病理探讨
Sudden Cardiac Death: Clinicopathologic Investigation of 51 Cases
【摘要】 <正> 心血管系统疾病从发病到死亡的时间,一般在30秒以内者称为暴死,数分钟到24小时内死亡者称为猝死。本文报告所收集心性猝死尸检51例的临床和病理资料。
【Abstract】 The morphological changes of heart in 51 cases of sudden cardiac death were studied. Among them 41 died of coronary haart diseases and 10 of other causes.In the coronary group, the following pathological characteristics of coronary arteries were observed:1. Obstructive thrombosis was found only in 9 cases, hence thrombosis was not the necessary factor for sudden death.2. The lesions were mostly multi-focal. In 73.% of cases atheromatous changes affected two or three main branches of coronary arteries at the same time. Not only the collateral circulation was influenced but also coronary spasm was easily induced thus providing a predisposing factor for sudden death.3. In 36.6% of cases mild coronary atherosclerotic lesion (Ⅰ°) was seen. If this type of lesion was not associated with coronary spasm, severe myocardial ischemia would unlikely to occur. Therefore in such cases death could have been prevented by effective emergency treatment.Histolygically, in addition to chronic myocardial fibrosis and scattered acute myocardial infarcts, the prominent features were the preinfarction changes including myocardial wavy deformation contraction bands, and myocardial fragmentation, etc., that might be considered as morphological bases of ventricular fibrillation. The pathogenesis of sudden cardiac death was discussed in accordance with the pathological findings.
- 【文献出处】 天津医药 ,Tianjin Medical Journal , 编辑部邮箱 ,1980年08期
- 【被引频次】3
- 【下载频次】20