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伤寒二十年来的变迁——140例临床分析

CHANGES OF THE CLINICAL PATTERNS OF TYPHOID IN THE RECENT TWENTY YEARS (FORM MARCH 1960 TO JUNE 1979)——ON ANALYSIS OF 140 CASES

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【作者】 潘孝彰; 孙涛;

【Author】 P AN XIAO-ZHANG, SUN TAO(Department of Infectious and Parasitological Diseases Hua Shan Hospital, Shanghai First Medical College, Shanghai)

【机构】 上海第一医学院传染病寄生虫病学教研组; 上海第一医学院传染病寄生虫病学教研组;

【摘要】 <正> 曾有作者提到目前国内伤寒的症状及体征已与过去不同,为了解近来伤寒的临床表现、实验室检查及药物疗效,我们分析了1960年以来的伤寒共140例,并与1958年前我院所见的826例作比较。

【Abstract】 We analysed the clinical manifestations of 140 oases of typhoid encountered in our hospital from March 1960 to June 1979 and compared them with 826 oases encountered before 1958. We found that the incidence among the youngsters of 12-20 years of age was greatly higher during 1960- 1979(71 oases, 50.7%) than that before 1958(265 oases, 32.08%) (P<0.01). The typical thphoid temperature curve was noticed to be 32.1%, while remittent and irregular fever 54.3%. before 1958 the corresponding figures were 63.3% and 27.1% (P<0.01) respectively. Epistaxis, deafness, abdominal pain and distention, diarrhea and/or constipation were found to be 2.1%, 3.6%, 15.7 %, 17,1 %, 31.5 % and 12.9 % (P<0.01) respectively, while delirium, coma,apathy and rose spots were encountered much less frequently than that before 1958 (P< 0.01). Pneumonia and menigitis were seen as well (P<0.05) though less often than before. The incidences of other complications, however were remained the same. The overall mortality of the present series was 0.71 %. Serum enzymes, including SGPT, AKP, LDH and MP, were elevated in all cases. The causative organisms, susceptibi-lites to ohloromyoetin and all the therapeutic measures, gave insignificant differences between 1960-1979 and before 1958.

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