【摘要】 <正> 近年来研究表明乙型肝炎表面抗原(HBsAg)阳性母亲有可能将乙型肝炎病毒(HBV)传给婴儿。有关母婴间传播HBV的机制目前尚有许多争论。使用高效价抗乙型肝炎表面抗原(抗-HBs)免疫球蛋白阻断母婴间传播 HBV的效果已被肯定,而低效价更多还原

【Abstract】 105 (5.0% )carriers of hepatitis B surface antigen (HBsAG) were screened from 2,087 pregnant women by reverse passive hemagglutination (RPHA). 27 (30.0%) HBsAg positive infants were detected in 6 months after birth from 90 infants of HBsAg oarr- ying mothers. Results indicated that the infants’ HBsAg condition was related to that of their mothers’ HBsAg, to the persistence of their mothers’ HBsAg condition including the titers of the corresponding antigen during six months after childbirth. However the positive incidences of infants’ HBsAg related neither to those of their umbilical cord serum, nor to those of their fathers’ and nor to the types of feeding and attending to their infants.42 HBsAg carrying pregnant women were randomly divided into two groups: in one group of 21 infants, 2 ml human placental γ-globulin with anti-HBs titer 1:16 by PHA were given within 72 hr after their deliveries, while the other 21 infants served as a control series. Folio wing-up observations were carried out twice respectively at 3 and 6 months after birth. The HBsAg positive rates and their geometrical mean titers of these two groups are statistically not significant. ,更多还原