【摘要】 <正> 内服大剂量某些药物中毒严重的患者,以往多采用利尿、对症、拮抗剂等方法治疗,效果不佳,死亡率高。我院用血液透析治疗六例大剂量药物中毒病人,获得满意效果。六例病人入院时均处于昏迷状态,其中一例并有肺水种、二例并有脑水肿,一例伴有呼吸功能不全,经紧急一、二次充分血液透析后全部逆转,在透析中并发症迅迅控制,病人在短期内神志逐渐清醒。更多还原

【Abstract】 Six cases of large dose hyminal, librieum, rimifon, or wintermin intoxication were treated by hemodialysis. Patients were all in comatous condition on admission. The cases treated early within 15 hours recovered promptly and became conscious at the end of dialysis. While the other cases with larger dose and delayed treatment usually required longer period of treatment, the longest one being 22 hours before they showed signs of recovery with rather active reflexes. Prolonged continuous dialysis was sometimes necessary in severe cases of intoxication in order to bring them back earlier, and was a safe measure without apparent syndrome of disequili brium or other untoward reaction.. Large amount of fluid infusion together with ultrafiltration might enhance the removal of drugs and to correct hemoconcentration which was frequently present resulted from diuretics.更多还原