【摘要】 <正> 本院于1978年初开始进行牛心包生物瓣膜的研制,经过动物实验及鉴定合格,同年5月开始临床应用,至1980年4月底共22例,初步报告如下。牛心包生物瓣的制造牛心包的制备取新宰成年牛的牛心包,先剔除心包表面的脂肪和疏松结缔组织,用Hank’s液漂洗三小时,以除去心包膜组织内的可溶性蛋白。将心包裁片,用0.65％戊二醛溶液固定二周,贮存备用。支架与包布用钛合金不锈钢制成三足等距的支架,足窄长,基底部连成环,三足与环垂直,环体与足体都有穿针孔。金属支架用特制的涤伦布包裹缝好。另用涤伦布作一缝合环,其口径与金属支架座环更多还原

【Abstract】 The process of the manufacture of Glutaraldehyde-stabilized bovine pericardial cardiac valves in our laboratory and their clinical applications (22 cases) were reported. Patients operated upon suffered from either rheumatic or congenital mitral or/and aortic valvular diseases. Most of their cardiac status were classified as Grade Ⅲ～Ⅳ. There were four early operative deaths (within the range of 30 days after operation). Two of them were very much debilitated preoperatively and died soon afterwards. This occurred in the early period of our work for lack of adequate experiences. Another late sudden death (2 months after the operation) was probably due to valvular thromboembolic complication. And the rest of cases have been followed for more than six months. They all are living and well with remarkable improvement in their cardiac function.更多还原