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D-葡萄糖-6-14C的制备与稳定性

Preparation and stability of D-glucose-6-14C

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【作者】 赵夏令; 郭子丽; 邓巧青; 刘景芝;

【Author】 Zhao Xia-ling Guo Zi-li Liu Jing-zhi Deng Qiao-qing (Shanghai Institute of Nuclear Research, Chinese Academy of Sciences)

【机构】 中科院上海原子核所; 中科院上海原子核所;

【摘要】 本文介绍用化学合成法制得D—葡萄糖—6—14C。产率按碳酸钡—14C计算为18.3%,比度为4.6mCi/mM。产品经鉴定为化学纯与放化纯,14C标记在第6位碳原子上。D—萄萄糖—6—C14在贮存中的稳定性也进行了研究。

【Abstract】 D-glucose-6-14C was prepared by chemical synthesis from 14C-barium carbonate. The yield was 18.3%, with specific activity of 4.6mCi/mM. The product was of high purity. The labeled position of 14C atom was proved by the degradation method. The stability of product in storing was also studied.

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