【摘要】 <正> 尾核属于锥体外系统,参与躯体运动的调节。但近来研究指出:尾核尚参与机体的感觉整合作用。而且,刺激尾核头部亦有镇痛和抑制疼痛反应的作用。在我们以往的工作中,曾观察到电针穴位对家兔尾核头部神经元自发放电活动的影响,可表现为激活、抑制或无变化三种类型。本工作进一步观察伤害性刺激对清醒家兔尾核头部自发活动的影响,以及电针能否改变伤害性刺激引起的放电型式。更多还原

【Abstract】 In this study spontaneous discharges of the single unit at the head of the caudate nucleus in the conscious and unrostrained rabbits were recorded with chronic microelectrode technique, Firstly, we observed the influences of the noxious stimuli, and then we observed whether electro-acupuncture may alter the responses to the noxious stimuli. In 60 experiments on 22 animals, we recorded spontaneous discharges of 102 neurons, the influences of noxious stimuli were observed on 58 units; of which 19 were activated; 21 inhibited And the rest showed no response. Among these 58 neurons, 30 had complete records of the effect of "Hegu" point electro-acupuncture. In the 13 neurons whose spontaneous activitities were activated by noxious stimuli, electro-acupuncture exhibited an inhibitory effect in 5 . where as in the 13 inhibited neurons, 3 were activated. The other 13 neurons showed little responses to both the noxious stimuli and electro-acupuncture. It seems that electro-acupuncture may reverse the influence of noxious stimuli on the spontaneous discharges of some neurons at the head of the caudate nucleus, and thus modulate the nociceptive inputs, and this may be one of the machanisms of acupuncture analgesia.更多还原