【摘要】 <正> 福建人体肺吸虫病例首先在厦门一位病人的痰里检到虫卵而被发现(Manson,1880)。福州郊区和屏南县棠口亦有病例报告(Maxwell,1931)。在福州、福清、莆田、长汀等地的虎、豹、狐、野猫、犬、家猫和猪等动物体内曾查得成虫(吴光,1937、1938;金德祥、1939;陈国忠,1941)。唐仲璋(1940)对福清林氏型和啮齿型等肺吸虫作生活史的比较研究。解放后陈捷先(1953)报道脑型病例。肖玉山等(1964)和吕建华(1965)又报告我省病更多还原

【Abstract】 The present article reports on the epidemiology and biology of paragonimiasis in Jien’ou district,Fujian Province.During 1975 a general survey together with studies on etiologic agents was undertaken in this area.As shown by the intrader-mal tests made on 3,067 pesants with antigens prepared from adult Paragonimus worms,there were 835 positives (36.85%) from the chosen endemic area.Biopsies made on 42 migratory subcutaneous nodules of these patients resulted in the obtaining of 5 immature adolescent worms from 5 nodules,while the other showed intense cellular infiltration and presence with Paragonimus eggs and Chareot-Leyden erystles in the lesions.529 stone crabs catching from the mountain streams of the endemic area were examined,and 232 of them (43.9%) were found to be infected with metacercarial cysts of Paragonimus.The number of cysts per crab varied from 1 to 1,115,with an average of 15.5.The majority of metacariae were in the muscles of pincers and walking legs (40-56%) and thorax (37-41%),and a small number of them were rarely attached to gills (0.44%).Three species of crabs were found to be naturally infected with cysts of Paragonimus..They are Sinopotamon sp.,Malayopotamon fukienensis and Nanhaipotamon angulatum.Three species of snails were incriminated as first intermediate hosts of Paragonimus in Jien’ou district.Semiculcopira toucheana Houde,was found infected with cercariae of P.westermani in one positive among 2,363 snails examined (0.04%) The second species,Tricula sp.was also found infected with the larval form of Paragonimus in 29 positive among 18,797 snails examined (0.15%).The third species,Pseudolythinella Jienouensis was also found infected in 215 positives of 40,222 snails examined (0.55%).These cercariae from both Tricula and Pseudolythinella were experimentally proved and identified as P.skrjabini.There were found two kinds of metacercarial cysts in crabs mentioned above.The first with small size (342μ) and thicker inner cyst-wall (18.16μ) is identffied and experimentally proved to be P.westermani.The second kind is larger (425μ),spherical in shape and with thin cyst-wall (11.4μ).These cysts were fed to laboratory-reared dogs and adult worms were secured which were identified as P.skrjabini.In some endemic areas of Jien’ou,most of the patients of paragonimiasis have migratory cutaneous nodules attributed to the infection with P.skrjabini,which do not normally develop in man.In the endemic area the people were accustomed to eat raw or partially-cooked crabs on the belief of their medicinal properties of curing arthritis inhabitants.Of 815 positives in our intradermal tests 611 (73.4%) answered positively on having eaten raw or partially cooked crabs.Records of Jienou-County Hospital showed that of 93 proved cases of paragonimiasis 81 of them (67%) also gave a pasitive answer.In the present study the carcases of 89 mammals belonging to 9 species were examined and only the leopard,cat,Felis bengalensis chinensis,was found naturally infected with Paragonimus.Two of eight leopard cats examined harboured 54 worms,of which 44 belonged to P.westermani,5 to P.skrjabini,while the rest were unidentified.Studies on their morphology are still in progress.更多还原