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鼻咽癌的血清学普查

SEROLOGICAL MASS SURVEY OF NASOPHARYNGEAL CARCINOMA

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【作者】 曾毅刘育希韦继能祝积松蔡绍霖王培中钟建明李瑞成潘文俊黎而介谭碧芳

【Author】 Zeng Yi Liu Yuxi Wei Jineng Zhu Jisong Cai Shaolin Wang Peizhong Zhong Jianming Li Ruicheng Pan Wenjun Li Erjie Tan Bifan Institute of Virology, Chinese Academy of Medical Sciences. Cancer Institute, Chinese Academy of Medical Sciences. People Hospital of Guangxi Zhuang Autonomous Region. Cancer Institute of Cangwu County.

【机构】 中国医学科学院病毒学研究所中国医学科学院肿瘤研究所广西壮族自治区人民医院广西苍梧县肿瘤研究所广西苍梧县肿瘤研究所

【摘要】 本文报告了用免疫酶法对广西苍梧县9个公社的91445人进行鼻咽癌血清学普查,VCA-IgA抗体阳性者1183人,阳性率1293.67/10万。抗体阳性者经临床和病理复查,发现鼻咽癌病人28例:Ⅰ期5例、Ⅱ期12例、Ⅲ期8例,Ⅳ期3例。低分化鳞癌、泡状核细胞癌和低分化腺癌分别为21、5和2例。作者还讨论了两次血清学普查的结果,再次证实免疫酶法用于鼻咽癌普查效果比较满意。

【Abstract】 A serological mass survey was carried out in 9 communes of Cangwu county of Guangxi Zhuang Autonomous Region, sera from 91445 people of age 30 and over in the general population were tested for IgA antibody to EB virus VCA by immunoenzymatic method. Among the 91445 persons, 1183 had IgA antibody to VCA with a GMT of 1 : 20.6.The positive rate was 1293.67/100,000. 77,88% of the antibody-positive persons had IgA antibody titer of (?) 1 : 10. Among the 1183 antibody-positive persons, 28 cases were diagnosed clinically and pathologically as nasopharyngeal carcinoma, 5 cases in stage Ⅰ, 12 in stage Ⅱ, 8 in stage Ⅲ and 3 in stage Ⅳ. The number of poorly differentiated squar-mous cell carcinoma, vesicular nucleus cell carcinoma and poorly differentiated adenocarcinoma were 21, 5 and 2 respectively. The results from twice serological mass surveys were also discussed. These results further confirmed that the immunoenzymatic method is useful for serological mass survey of nasopharyngeal carcinoma.

  • 【文献出处】 中国医学科学院学报 ,Acta Academiae Medicinae Sinicae , 编辑部邮箱 ,1979年02期
  • 【被引频次】41
  • 【下载频次】79
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