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止血纤维的实验研究

EXPERIMENTAL STUDIES OF STYPTIC FIBRES

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【作者】 郝文博刘杰文张敬芬张顺祥

【Author】 Hao Wenbo Liu Jiewen Zhang Jingfen Zhang Shunxiang( Institute of Hematology, Chinese Academy of Medical Sciences )

【机构】 中国医学科学院血液学研究所中国医学科学院血液学研究所

【摘要】 本文报告了止血纤维一些实验研究的结果。证明该药对动物脏器手术创面的止血效果迅速、可靠;对四种实验动物的局部和全身未见显著毒性作用;可以逐渐被组织消化和吸收。作者还对止血纤维的作用原理进行了初步探讨。

【Abstract】 The styptic fibres are made by spinning a mixture of gelatin and a synthetic low molecular polymer. The fibres are soaked in a solution of herbal medicine. It is of good chemical stability, with broad medicinal sources and convenient for use.More than 2000 tests done in 412 experimental animals have shown that the styptic effect of the fibres are rapid and reliable. According to the method used in this paper, the average styptic time is 1.5 min. on partial splenectomy and about 4 min. on femoral arteriotomy of the dogs. The examinations of acute, subacute and chronic toxicity are carried out by putting the styptic fibres in the muscles, livers, spleens and abdominal cavities of four kinds of animals. There was no systemic or local adverse reaction observed in these experimental animals. Pathological examinations under the light and electron microscopy revealed that the fibres could be digested and absorbed gradually by the organisms.

  • 【文献出处】 中国医学科学院学报 ,Acta Academiae Medicinae Sinicae , 编辑部邮箱 ,1979年02期
  • 【被引频次】2
  • 【下载频次】40
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