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二二三乳剂处方的改进

IMPROVED FORMULA OF DDT EMULSION

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【作者】 王鸿辰;

【Author】 WANG HUANG-CHEN (Emulsion Group, Department of Pharmacy, Peking Medical College)

【机构】 北京医学院药学系药剂教研组乳剂小组;

【摘要】 <正> 农药和卫生防疫用的二二三(二氯二苯三氯乙烷)乳剂要求浓度在25%以上,以利运输和貯存.目前国内生产的乳剂貯备液是一种油溶液,其中含苯、樟油、松节油等有机溶剂占50%.为了节约有机溶剂的消耗,我们试制二二三水油两相乳剂,用水代替其中部分有机溶剂.由于乳化剂和乳化工具的缺乏,目前制备此项乳剂实有困难.因乳剂中二二三含量高,貯存时易破坏和产生结晶.我们曾利用机械搅拌法试制多种乳化剂,均不能

【Abstract】 The liquid whistle ultrasonic emulsifying equipment was used for making DDT emulsions. The favourable temperature of treatment was found to be at 40-48℃, and the time of treatment was 30 minutes. Stabilities of emulsions under influences of tem- perature, pH and electrolytes were studied. The sulphite liquor (from the Sulphite pulp process) as an emulsifying agent produced the most stable emulsion. This emulsifying agent was found to be less surface active, and more resistant to the change of pH and to electrolytes than Turkey red oil, but to produce stronger interfacial film. Therefore the strength of interfacial film and chemical nature of the emulsifying agents were considered to be important factors affecting the stability of emulsions.

  • 【文献出处】 药学学报 ,Acta Pharmaceutica Sinica , 编辑部邮箱 ,1965年05期
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