【摘要】 将相应的烷基二氯化胂及相邻和相同的二巰基化合物直接缩合,不用任何溶剂,得到相应的间二硫砷五环(Ⅱ)及间二硫砷六环(Ⅲ),企图获得七元环的硫醇砷盐,则未成功。若干二氯化胂及二巯基化合物的制备法,在操作程序上有所改变。更多还原

【Abstract】 Cyclic arsenic mercaptides (such as Ⅱ and Ⅲ) were synthesized as potential chemotherapeutic agent in the treatment of leukemia or tumour. Various dithiols and dichloroarsines were condensed without any solvent, to form the ring compounds of arsenic (Ⅱ and Ⅲ). Condensation of dithiols with arsenoxides could also give the desired products. Attempts to prepare the seven-membered cyclic mercaptides, by treating 1,4-butane dithiol with various dichloroarsines, were not, unsuccessful. The preparation of several aliphatic dithiols and dichloroarsines was also described. Some modifications of the processes had been made. Experimental chemotherapeutic results will be reported elsewhere.更多还原