【摘要】 本文证实国内某些工厂四环素生产中的异常发酵现象是由噬菌体所引起的,从一些工厂中分离到噬菌体SA1、SA2、SA3、SA4和SA5。对它们的噬菌斑进行了描述,在血清分型、寄主范围、热失活、pH值的稳定性测定方面都进行了工作,同时在电镜下观察了形态和测量了大小。我们认为这些噬菌体都是属于同一血清型,形态基本相似,大小差异不显著,对pH值有广泛的适应性,对热抵抗力较强,但在这些特征和寄主范围内却存在一定差异。这类噬菌体和已知的金色链霉菌噬菌体是不相同的。更多还原

【Abstract】 It has been proved that abnormalfermentation in tetracycline productionby Streptomyces aureofaciens in our coun-try is mainly due to phage infection.Phages SA1, SA2, SA3, SA4, and SA5,were isolated from their fermentationfactories. These phages were characterizedin following aspects: serological neutra-lization reaction, host-range relationship,thermal inactivation and stability at differ-ent pH values. Morphology of five phageswas studied in the electron microscopeand their dimensions were determined. It is concluded that phages SA1, SA2,SA3, SA4, and SA5 all belong to thesame sero type. Their morphology anddimensions are very similar. These fivephags are stable over a wide range of pH.They are also thermostable, withstandingelevated temperatures. However, theyare also sufficiently different in thesecharacterizations and host-range relation-ship. Phages SA1, SA2, SA3, SA4 andSA5 are different from all known phagesattacking Streptomyces aureofaciens.更多还原