【摘要】 <正>晚期血吸虫病患者往往出现血浆清蛋白降低以及清蛋白与球蛋白比例倒置的症状[l一3],这些症状的出现可能由于下面几种原因所引起:患者胃钠不佳,又握常腹泻以致身体摄取食物蛋白质的分量不足;患者肝功能受损,更多还原

【Abstract】 Rabbits infected with Shistosoma Japonicum for three months were shown to have their plasma albumin concentration significantly decreased,and the concentration ratio of plasma albumin and globulin was found to be reversed.The latter result is very similar to that foand in patients suffering from the same disease. The amount of peritoneally or orally administered S~35-methionine incorporated into albamin per unit volume of plasma in an infected rabbit was about one-half of that in a normal animal,but the incorooration of the amino-acid into plasma globulin was increased at the same time.The turnover rates of plasma albumin and globulin in the diseased animals were abnormally low.Both the infected and normal rabbits absorbed more thaft 97% of orally administered methionine.These results indicate that the ability of the intestine to absorb digested proteins in late stage schistosomiasis is not impaired and that the hypoalbuminemia of the disease is mainly due to the functional damage of the liver for plasma albamin synthesis.更多还原