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神经系统刺激物(巴豆油)对于小白鼠实验性流行性乙型脑炎感染的抵抗力的影响

THE EFFECT OF A NERVOUS SYSTEM IRRITANT(CROTON OIL)ON RESISTANCE TO EXPERIMENTAL JAPANESE B ENCEPHALITIS INFECTION OF MICE

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【作者】 何德侯健存林迪安娜郑永芳娄艾琳

【Author】 HO TE HOU CHEN-TSWEN LIN TI-ANA CHENG YUNG-FANG LO AI-LIN (Department of Physiology,Chinese Academy of Medical Sciences,Peking)

【机构】 中国医学科学院生理系中国医学科学院生理系 北京北京

【摘要】 <正> 传染性疾病的发生及其严重程度取决于病原的有害影响和宿主的保护性反应相互对抗的结果。可是,虽然在理论上一般都公认上述见解的正确性,但在微生物学实践上绝大部分工作却针对着有害微生物的本质和特性进行研究。对于机体在病原侵入前的状态的详细分析反而相对地缺乏。

【Abstract】 A single subcutaneous injection of croton oil(5% mixture in paraffin oil)given to white mice the same day,or 1 or 2 days before injection of Japanese B encephalitis virus, reduced mortality and prolonged survival time of these animals in comparison with controls. Difference of mortality of the treated animals and controls was statistically significant,higher levels of reliability being attained in animals given croton oil on the same day or one day before virus than in those injected with oil two days prior to virus. The effects of croton oil on the nervous system is invoked to explain the results,but the pos- sibility of an influence of croton oil on virus potency is also discussed.

【关键词】 巴豆油保护性反应刺激物死亡动物著意同天右侧腹服重一侗封育
  • 【文献出处】 生理学报 ,Acta Physiologica Sinica , 编辑部邮箱 ,1957年02期
  • 【被引频次】3
  • 【下载频次】23
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