【摘要】 <正> 近几年来由于脑内阿片受体和内沅性吗啡样物质研究的进(?),支持了弹经系统中具有内在性抗病系统的设想,内沅性吗啡样物质与针刺镇痛的关系遂成为科学工作首关注的问题。1977年,上海市人体针刺镇痛实验协作组用伩号侦(宀叉)法证明纳洛酮可以部分阻断针刺镇痛效应,同外也有报导纳洛酮可以阻断针刺人体穴位对电刺激牙髓的镇痛作用。在动物实验上,纳洛酮也能阻断小鼠电针穴位引起的镇痛作用,对家兔更多还原

【Abstract】 Experiments were conducted on the conscious rabbits. Vascular reaction of the hind leg was recorded with an impedance plethysmograph. Vasodilatation was usually recorded when the urether or bladder was stretched by a weight of20-50 gm through a pulley system. The vasodilatatory reaction was usually inhibited by needling "Jen-Chung" (人中) and "Szu-Pai" (四白) points.The acupuncture inhibition was found to be reversed after i.v. of the narcotic antagonist nalorphine in 9 of 12 rabbits. The rate of reversal ranged from 12.34-88.2%, with an average of 41%. The time of reversal lasted for 3 -15 minutes with a peak at 6 minutes. Statistically the reversing effect of nalorphine on the acupuncture inhibition was significant (p<0.0025), while the control group of saline injection( 6 subjects) had no effect on acupuncture inhibition.It is concluded that nalorphine partly reversed the acupuncture inhibition of the vasomotor reaction to visceral stretch.更多还原