【摘要】 <正> 引起人类呼吸道感染的病毒种类颇多,其中流感病毒的研究较为详尽,这是由于流感的流行传播极为迅速广泛,历史上曾有多次发展成为世界性者。腺病毒感染虽不如此猖獗,但自1953年 Rowe 氏等发现后,继为 Hilleman氏等证实其病原性,以后世界各地均有由腺病毒引起疾病的报告,特别是腺病毒能引起严重的幼儿肺炎及新兵中的流行,因此更值得我们重视。更多还原

【Abstract】 By means of tissue culture,using monolayer cell of human embryonic kidney,human amnion tissue and HeLa cell,12 strains(6.4%)of ade- novirus were isolated from throat swabs taken from 188 cases of infantile pneumonia occuring from autumn 1959 up to the end of 1961 in Shanghai district.Six of the 12 strains(adenovirus)were studied by neutralization test with type specific antisera;2 strains each were found to belong to type 3 and type 7,1 to type 4 and l strain was unidentifi- ed.Fifty-five pairs of early and convalescent sera were subjected to complement fixation test.The antibody titre increased 2-4 times or more in 16 cases(29.1%).In 42 eases of the same group, complement fixation test against influenza vi- ruses A and B was also performed,and only 3 (7.1%)had 4 times increase of titre against influenza virus A.The serological test of one patient was positive both against adenovirus and influenza virus,indicating that he had mixed infection. During the same period,252 specimens of serum were taken from patients aged 0 to 60 years old and not suffering from respiratory infection.Each of these specimens represents pooled serum from 20-40 patients of each age group.The result of complement fixation test using adenovirus type 1 as antigen suggested that adenovirus infection was widely dissemi- nated among different age groups.The average antibody titre was somewhat higher among the children(1:52)than that in adults(1:25.6).The adenovirus infection rate in the 2-4 years old age group was the highest.The infection was more prevalent during autumn-winter than in spring-summer seasons.The data obtained sug- gested that the adenovirus infection appeared in epidemic form among the children around Oct. 1959.更多还原