【摘要】 一个两周岁的女性婴儿脑,在左侧大脑半球的额顶区有广大的孔洞,与扩大的侧脑室相通。左侧的纹状体增大;大脑脚、脑桥和延髓的锥体显著萎缩。在显微镜下观察,左侧的主要异变如下:1.锥体束不存在。2.黑质大过常侧数倍,延伸到大脑脚底的前缘。3.红核上下加长,面积亦大过常侧。4.丘脑底核、苍白球、壳核和尾状核的形体,均呈格外的发展,大过常侧数倍。5.高倍镜下,在这些增大的结构中,均看到神经细胞的正常分布,非胶质增生。由于锥体本系缺损,锥体外系就格外发展。把这些变化与临床症状参证,可知后者在机能上实在起了代偿作用。更多还原

【Abstract】 The brain of a porencephalous girl of two years old was studied.An extensive cavity was found in the fronto-parieal region of the left hemisphere.She showed no paralysis of the right upper and lower extremities,yet fine movements of the hand and normal standing were impossible.Serial sections of the brain stem were examined.The right pyramidal tract was found to be normal,but the left one was lacking.On the other hand,the extrapyramidal nuclei showed compensatory hypertrophy on the affected side.These included the substantia nigra,red nucleus,subthalamic nucleus,globus pallidus,caudate and putamen.The results was in harmony with the clinical observations;the hypertrophied structures have compensated the defect of the pyramidal system.更多还原