【摘要】 本文对四川肺吸虫进行了一系列补充观察和研究,进一步证明四川肺吸虫确是一个能使人致病的独立新种,与陈氏1960年报告的斯氏肺吸虫截然不同。科学根据概括如下: 1.虫体宽长比,轻压标本平均为1:2.8,未压标本平均为1:3.3,与斯氏1:2.2者不同。 2.卵巢分枝比卫氏及克氏者复杂,比大平及怡乐村者简单,为两者间的过渡型。 3.睾丸在自然形态上为长条状,呈“天”或“王”字形,纵行、并列,侧立于虫体后1/3处。 4.皮棘为混生型,即在虫体前部为单生,向后则丛生者渐增多,介于卫氏、克氏单生型及大平、怡乐村丛生型间的过渡型。本虫皮棘在脱囊蚴为单生,在童虫有2—3并生者,在成虫则为5—6丛生,此种演变可能与虫龄有关,值得注意。与斯氏单生型绝不相同。 5.从人工感染猫、猴和果子狸的粪便中以及大白鼠肺囊内所获得的340个虫卵来看,其大小平均为82.4×48.4微米,宽长比为1:1.71。其中两只果子狸粪便所得虫卵的大小平均值分别为84.1×50.3及82.4×47.2微米,与陈氏1960年报告的从果狸获得斯氏肺吸虫虫卵大小为71×48微米者有明显差别。 本虫开始排卵时间在家猫接种后55—64天,每虫平均排卵1,732—6,662个/天。 6.本种虫卵在28℃温水中经21—23天可孵出毛蚴。毛蚴四列纤毛板排列为6.7.3.1。 7.至此,四川肺吸虫成虫形态,第一更多还原

【Abstract】 The present paper records the results of our further studies on Paragonmus sze-chuanensis which is pathogenic to man. The results obtained confirm that P. szechuanensis is a new and distinct, species of lung fluke, being very much different from P. skrjabini. The scientific evidences may be listed below.1. The ratio of breadth to length of the adult P. szechuanensis is 1: 2.8 for slightly pressed specimens, and 1: 3.3 for unpressed specimens, being very much different from the figure of 1: 2.2, as given by Chen for P. skrjabini.2. The branching of the ovary of P. szechuanensis is more complicated than that of P. westermani-P. kellicotti group and simpler than that of P. ohirai-P. iloktsue-nensis group, representing a transitional condition between these 2 groups of lung flukes.3. The testes of this flake are long and narrow, being situated sidewise dorsally on the posterior 1/3 of the worm, and having a characteristic shape resembling that of the Chinese characters "王" and "天".4. The cuticular spines belong to the "mixed-growth pattern". That is to say, they appear as single spines in the anterior 1/3 of the worm and gradually assume the ’’group-growth pattern" from the level of the middle 1/3, being increasingly preponderant toward the posterior 1/3 of the parasite. This "mixed-growth pattern" of the cuticular spines of P. szechuanensis occupies a transitional position between the single-growth pattern of the P. westermani-P. kellicotti group on the one hand, and the group-growth pattern of the P. ohirai-P. iloktsuenensis group on the other. They are very much different from the "single-growth pattern" cuticular spines of P. skrjabini.The cuticular spines of P. szechuanensis occur as "single-growth" ones in the excys-ted metacercariae, as pairs or triples ia its adolescents, and as "mixed-growth" ones in its adult form. This variation in the pattern of the cuticular spines may be related to the developmental stage or to the age of the parasite and is worthy of note.5. Measurements of 340 ova from the stools of laboratory-infected cats, monkeys and Paguma larvata and from the lung-cysts of white rats similarly infected give an average size of 82.7 × 48.4* with a breadth to length ratio of 1:1.71. The ova from 2 infected Paguma larvata average 84.1 × 50.3μ and 82.4 × 47.2μ respectively in size. There is a marked difference between these figures and those given by Chen as 71 ×48 μ for the ova of P. skrjabini.P. szechuanensis begins to pass ova in the stools of laboratory-infected cats 55-64 days after infection with an average output of 1,732-6,662 ova daily.6. In water at a temperature of 28× the miracidia of P. szechuanensis hatch out after 21-23 days of incubation of the ova of the said fluke. The epithelial layer or plate of the miracidium is arranged in 4 rows, from head to tail of the organism, being 6 in number in the 1st, 7 in the 2nd, 3 in the 3rd and 1 in the 4th rows respectively.7. This paper has also discussed the salient features of P. szechuanensis by which the latter species may be distinguishable from P. fukienensis, P. tuanshanensis, P. yun-nanensis, P. miyazaki, P, menlaensis, P. africanus, and P. uterobilateralis.8. Up to the present time, preliminary studies on the morphology of the adults of P, szechuanensis. the natural and laboratory infection of the first intermediate host (Tricula humida Heude), and the second intermediate host (2 species of..Potamon crabs) as well as the morphology of the various larval stages-miracidia, sporocysts, rediae, metacercariae and excyst-metacercariae of this fluke have been completed. We have endeavored to make clear the salient features of the clinical manifestations, pathologic changes, geographic epidemiology, as well as other aspects of this new disease entity-paragonimiasis szechuanensis-caused by this new lung fluke P. szechuanensis.As a result of research studies made by us in recent years, it has now been com-firmed that Paragonimus szechuanensis is a new and distinct species of lung fluke pathogenic to man. But since 1961-1963, the authors of Parago更多还原