【作者】 李盛；

【导师】 石冰；

【作者基本信息】 四川大学 ， 口腔临床医学， 2006， 博士

【摘要】 先天性唇腭裂是我国发病率最高的出生缺陷，虽然可以通过外科手术进行治疗，并通过与其它治疗手段联合干预，来达到纠正畸形的目的，但是由于这种先天畸形在其表现形式上多种多样，学者们对其认识能力的限制以及既往各种治疗方式的理论基础和治疗观念相对落后，使得手术效果不稳定，术后形态难以令人满意，因此有必要对单侧完全性唇腭裂的畸形特征进行深入研究，并在此基础上分析既往各种术式的几何学原理，发展新的手术方法，才能进一步提高这种先天畸形的治疗效果。 以往有研究发现，在单侧完全性唇腭裂既存在上唇组织缺损，也存在组织移位，但是畸形变异的程度和范围却没有具体的分析，而且各个畸形特征之间的关系也少有报道。对畸形认识的不全面就使各种手术方法没有整体的观点和联系的观点，往往只针对某一具体的畸形进行干预，虽然纠正了局部的畸形，但却就造成了局部与整体的不协调。因此，对单侧完全性唇腭裂畸形特征的研究，就有助于我们更加全面协调地对其进行整体水平的治疗。 在具体的术式设计过程中，几何学的原理虽然一直被用来指导术式的设计，但是早期的应用都比较简单和直接，学者们没有比较深入的寻找几何学的规律和特征，因而在运用几何学原理的时候也都是根据各自的经验和习惯，主观随意性比较大，术后效果大多不稳定，有时术后遗留的畸形更加难以处理。因此，不断探索和恰当地运用正确的几何学原理，对形成新的术式、获更多还原

【Abstract】 Congenital cleft lip and palate is the most common birth defect in China. Although surgical operation and other relative treatment could repair the deformity, the result is not consistently stable and satisfying because of the variety of deformity and the limitation of the researchers along with the old theories. It’s necessary to make efforts to research characteristics of the deformity, analysis the geometry principle of methods. On the base of these research and analysis, it’s necessary to develop new protocol of repair of unilateral cleft lip and palate(UCLP).The research have demonstrated the tissue deficiency and tissue distort of the UCLP, but the variety of the deficiency and distort has not been covered, nor the relationship between the detail of the deformity. The lack of understand of the deformity must lead to treatment without comprehensive viewpoint. The local deformity may be corrected when the overall harmony is destroyed. So, the research of characteristics will help to improve the level of treatment.Although it was utilized to direct the design of the incision, the geometry principle is simple and improperly. Without comprehensive understand of it, researchers performed the repair according to the experience and habit. This made the result unstable and even worse; the deformity after the primary operation is difficult to be corrected when it is time to have revision.Our study try to resolve these problems and researched the characteristics of更多还原