【摘要】 采用水热法合成二氧化铈（CeO₂）修饰的羟基氧化铁（FeOOH），得到纳米材料CeO₂/FeOOH。CeO₂/FeOOH具有类过氧化物酶活性，可以催化过氧化氢（H₂O₂）分解产生羟自由基（·OH）和超氧阴离子自由基（O2-·），将3,3’,5,5’-四甲基联苯胺（3,3’,5,5’-tetramethylbenzidine,TMB）氧化为蓝色的氧化TMB（oxidized TMB,ox-TMB）。基于此，构建基于CeO₂/FeOOH纳米酶的H₂O₂比色传感器。结果表明：该比色传感器对H₂O₂显示出高灵敏度响应，检测限为3.92μmol/L，检测范围为10～1 000μmol/L。此外，该传感器可用于泡椒凤爪中H₂O₂的快速检测，其中，H₂O₂加标回收率为90.59%～93.42%，相对标准偏差≤4.25%，具有灵敏、准确、快速和简便等优势。更多还原

【Abstract】 In this study, an innovative cerium dioxide-modified iron oxyhydroxide（CeO₂/FeOOH） nanozyme with peroxidase-like activity was synthesized by one-step hydrothermal method. The CeO₂/FeOOH nanozyme could catalyze the decomposition of hydrogen peroxide（H₂O₂） to produce hydroxyl and superoxide anion radicals, which in turn could oxidize 3,3’,5,5’-tetramethylbenzidine（TMB） to produce a blue substance（oxidized TMB, ox-TMB）. Based on this, a CeO₂/FeOOH-based colorimetric sensor was constructed for the detection of H₂O₂. The results showed that the colorimetric sensor exhibited a highly sensitive response to H₂O₂ with a detection limit of 3.92 μmol/L and a linear range of 10 to 1 000 μmol/L. The recoveries for spiked samples ranged from 90.59% to 93.42% with relative standard deviations（RSDs）not more than 4.25%. The developed method had the advantages of high sensitivity, high accuracy, speediness and simplicity.更多还原